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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRN2
All Species:
16.67
Human Site:
Y831
Identified Species:
26.19
UniProt:
Q9H0D6
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0D6
NP_036387.2
950
108582
Y831
R
G
S
G
T
G
I
Y
S
N
A
A
P
P
P
Chimpanzee
Pan troglodytes
XP_514546
950
108522
Y831
R
G
S
G
T
G
I
Y
S
N
A
A
P
P
P
Rhesus Macaque
Macaca mulatta
XP_001094734
961
109718
Y842
R
G
S
G
T
G
I
Y
S
N
A
A
P
P
P
Dog
Lupus familis
XP_534324
950
108331
Y831
R
G
T
G
A
G
V
Y
G
N
A
A
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBR1
951
108669
Y831
R
G
S
G
T
S
V
Y
T
N
T
A
L
P
P
Rat
Rattus norvegicus
NP_001102066
561
63850
L459
Q
G
N
V
Y
R
P
L
L
R
G
Q
A
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505862
950
108030
L831
R
G
G
S
G
T
G
L
Y
S
N
A
A
P
P
Chicken
Gallus gallus
Q5ZIP4
949
108524
M831
R
E
R
G
M
P
G
M
Y
A
N
A
V
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM71
908
103942
G802
R
N
Q
Q
G
G
G
G
N
G
G
G
G
G
G
Honey Bee
Apis mellifera
XP_392371
860
99367
C754
I
R
N
N
K
V
Y
C
I
K
F
R
D
P
K
Nematode Worm
Caenorhab. elegans
Q9U299
975
110109
G858
G
G
G
G
G
G
G
G
Y
R
G
N
S
Y
D
Sea Urchin
Strong. purpuratus
XP_795068
1073
120270
P898
Q
L
L
Q
G
A
V
P
C
S
S
Q
S
H
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FQ03
1020
116807
P894
P
G
Y
G
Y
N
P
P
Q
Y
V
P
P
I
P
Baker's Yeast
Sacchar. cerevisiae
Q02792
1006
115915
D898
R
R
W
N
F
G
N
D
L
K
Q
N
I
V
P
Red Bread Mold
Neurospora crassa
Q8WZX5
1072
118291
R916
G
G
G
R
G
G
G
R
G
G
Y
G
G
N
G
Conservation
Percent
Protein Identity:
100
99.7
97.6
98
N.A.
96
56.2
N.A.
91.1
82.9
N.A.
N.A.
N.A.
51.2
54
50.5
52.5
Protein Similarity:
100
99.8
98
99
N.A.
97
57.6
N.A.
95.4
90.5
N.A.
N.A.
N.A.
63.2
66.5
63.7
63.4
P-Site Identity:
100
100
100
73.3
N.A.
66.6
6.6
N.A.
33.3
26.6
N.A.
N.A.
N.A.
13.3
6.6
20
0
P-Site Similarity:
100
100
100
86.6
N.A.
80
20
N.A.
40
26.6
N.A.
N.A.
N.A.
20
13.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.6
40.5
40.8
Protein Similarity:
N.A.
N.A.
N.A.
58
57.4
56.1
P-Site Identity:
N.A.
N.A.
N.A.
26.6
20
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
0
0
0
7
27
47
14
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
0
0
0
0
7
0
7
% D
% Glu:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
7
% F
% Gly:
14
67
20
54
34
54
34
14
14
14
20
14
14
7
14
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
7
0
0
0
0
0
20
0
7
0
0
0
7
7
7
% I
% Lys:
0
0
0
0
7
0
0
0
0
14
0
0
0
0
7
% K
% Leu:
0
7
7
0
0
0
0
14
14
0
0
0
7
0
7
% L
% Met:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
7
14
14
0
7
7
0
7
34
14
14
0
7
0
% N
% Pro:
7
0
0
0
0
7
14
14
0
0
0
7
34
54
54
% P
% Gln:
14
0
7
14
0
0
0
0
7
0
7
14
0
7
0
% Q
% Arg:
60
14
7
7
0
7
0
7
0
14
0
7
0
0
0
% R
% Ser:
0
0
27
7
0
7
0
0
20
14
7
0
14
0
0
% S
% Thr:
0
0
7
0
27
7
0
0
7
0
7
0
0
0
0
% T
% Val:
0
0
0
7
0
7
20
0
0
0
7
0
7
7
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
14
0
7
34
20
7
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _